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Wednesday: ARCH's $1.5B China NewCo and Jazz's 26.4-month OS

Aug 26, 2026

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4 min read

Wednesday: ARCH's $1.5B China NewCo and Jazz's 26.4-month OS

Plus: Zymeworks banks $250M and falls 7%. Bristol Myers walks.

Newsletter

Tuesday: Merck's 3rd IRA loss and a 23% gene therapy gut-punch

Aug 25, 2026

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5 min read

Tuesday: Merck's 3rd IRA loss and a 23% gene therapy gut-punch

Alzheimer's gets a blood test, Regenxbio gets five bad MRIs, Munich opens Friday.

Newsletter

Monday: Roche pays $190M up front to keep the muscle on

Aug 24, 2026

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4 min read

Monday: Roche pays $190M up front to keep the muscle on

Non-incretin obesity, a GOP letter aimed at China trial data, and Capricor’s PDUFA comes and goes.

Newsletter

Friday: BMS rents AI models, Amgen walks from $500M in milestones

Aug 21, 2026

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4 min read

Friday: BMS rents AI models, Amgen walks from $500M in milestones

Roche commits $750M to a plant that won't fill a syringe until 2031.

Newsletter

Thursday: Moderna's 177% day and two first-ever approvals

Aug 20, 2026

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4 min read

Thursday: Moderna's 177% day and two first-ever approvals

Moderna adds $44B of market cap in a session, and the FDA hands out two firsts.

Newsletter

Wednesday: Trump's FDA pick and BioMarin's $275M bone bet

Aug 19, 2026

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4 min read

Wednesday: Trump's FDA pick and BioMarin's $275M bone bet

Overton heads for a Senate fight, and a third China trial death surfaces.

Newsletter

Tuesday: EyePoint's 70% wipeout hits wet AMD

Aug 18, 2026

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4 min read

Tuesday: EyePoint's 70% wipeout hits wet AMD

Duravyu's primary miss, a PD-1/VEGF curve that shrank, and AstraZeneca finally printing a win.

Newsletter

Monday: AstraZeneca's 895-patient bispecific bet folds

Aug 17, 2026

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4 min read

Monday: AstraZeneca's 895-patient bispecific bet folds

Capricor doubles on an FDA reprieve, and Redx backs into Nasdaq with $125M.

Newsletter

Friday: BMS lands the first CELMoD at $29,500 a cycle

Aug 14, 2026

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4 min read

Friday: BMS lands the first CELMoD at $29,500 a cycle

Zipalertinib clears Phase 3, and the FDA puts a price on where you run Phase 1.

Newsletter

Thursday: Definium's LSD pill goes 2-for-2 in Phase 3

Aug 13, 2026

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4 min read

Thursday: Definium's LSD pill goes 2-for-2 in Phase 3

Plus: PTC raids the Sangamo estate for $111M, and Vykat XR draws heat.

Newsletter

Wednesday: Zydus options a $475M shot at alpha-1

Aug 12, 2026

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4 min read

Wednesday: Zydus options a $475M shot at alpha-1

Three drugmakers take Illinois to court, and crossover money backs an FSHD editor.

Newsletter

Tuesday: Jazz pays $820M upfront for Actio

Aug 11, 2026

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4 min read

Tuesday: Jazz pays $820M upfront for Actio

Jazz swings for rare epilepsy, Trump targets childhood shots, and Sionna hands Vertex a free pass.

Newsletter

Monday: DC drafts brakes on $136B of China deal flow

Aug 10, 2026

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5 min read

Monday: DC drafts brakes on $136B of China deal flow

Grail's failed test finally gets a date with an FDA panel.

Newsletter

Friday: Latigo prices $345.6M, Replimune clears the FDA

Aug 7, 2026

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4 min read

Friday: Latigo prices $345.6M, Replimune clears the FDA

Two rejections, one adcomm, one approval — plus $450M for a drug that reads out in 2029.

Newsletter

Thursday: A $400B merger dies, 2 FDA nods land

Aug 6, 2026

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5 min read

Thursday: A $400B merger dies, 2 FDA nods land

Reuters says the AstraZeneca-Bristol Myers talks are off. Also: two IPOs price.

Newsletter

Wednesday: PrEP clears $1B, KKR clears $5.7B

Aug 5, 2026

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4 min read

Wednesday: PrEP clears $1B, KKR clears $5.7B

Hinge expands into digestive care, Gilead's Yeztugo beats, and Merck leans harder into the Keytruda combo play.

Newsletter

Tuesday: Curium's $8B bid for the PSMA scan business

Aug 4, 2026

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4 min read

Tuesday: Curium's $8B bid for the PSMA scan business

Curium takes Lantheus private, Pathos writes a $125M check, and Jazz raises the year.

Newsletter

Monday: AstraZeneca and Bristol Myers float a $400B merger

Aug 3, 2026

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4 min read

Monday: AstraZeneca and Bristol Myers float a $400B merger

Novo’s ZEUS misses on 6,300 patients. Apnimed’s debut pops 56%.

Newsletter

Friday: Replimune gets its 10-3 reset

Jul 31, 2026

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4 min read

Friday: Replimune gets its 10-3 reset

FDA advisers back Replimune, Alnylam gets cut down to size, and the first pharma tariffs skip their Friday deadline.

Newsletter

Thursday: J&J pays $785M upfront for in vivo CAR-T

Jul 30, 2026

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4 min read

Thursday: J&J pays $785M upfront for in vivo CAR-T

J&J swings for Sail, Capricor gets a 9-3 adcomm rebuke, and reverse mergers still find $478M.

Newsletter

Wednesday: J&J tries to cap a $5.5B talc overhang

Jul 29, 2026

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4 min read

Wednesday: J&J tries to cap a $5.5B talc overhang

J&J writes a $5.5B cheque to close the talc book, Altimmune's GLP-1 lands in the drinking clinic, and Yokohama sells out before it opens.

Newsletter

Tuesday: AstraZeneca eyes ~$5B for its ADC as Ultomiris flops

Jul 28, 2026

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4 min read

Tuesday: AstraZeneca eyes ~$5B for its ADC as Ultomiris flops

An OS win and a rare-disease faceplant for AstraZeneca, an FDA ambush on Capricor a day before its panel, and MapLight's 66% haircut on the Cobenfy comp.

Newsletter

Monday: argenx's $2.2B Forte grab reopens the M&A window

Jul 27, 2026

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4 min read

Monday: argenx's $2.2B Forte grab reopens the M&A window

argenx bags an anti-CD122 antibody for $2.2B, and CHMP splits its rare-disease verdicts.

Newsletter

Friday: Lilly's triple-G lands 22.6% and misses on MACE

Jul 24, 2026

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4 min read

Friday: Lilly's triple-G lands 22.6% and misses on MACE

Retatrutide clears the bar but not the one that mattered, J&J posts an 0.11, and gene editing prices an IPO.

Newsletter

Thursday: GSK's $10.6B Nuvalent bet pays off in a week

Jul 23, 2026

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4 min read

Thursday: GSK's $10.6B Nuvalent bet pays off in a week

FDA cleared GSK's $10.6B Nuvalent asset two months early. Arrowhead cut triglycerides 81%.

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